MLK3 regulates fMLP-stimulated neutrophil motility
نویسندگان
چکیده
منابع مشابه
Induced, selective proteolysis of MLK3 negatively regulates MLK3/JNK signalling.
MLK3 (mixed lineage kinase 3) is a MAP3K [MAPK (mitogen-activated protein kinase) kinase kinase] that activates multiple MAPK pathways, including the JNK (c-Jun N-terminal kinase) pathway. Immunoblotting of lysates from cells ectopically expressing active MLK3 revealed an additional immunoreactive band corresponding to a CTF (C-terminal fragment) of MLK3. In the present paper we provide evidenc...
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ژورنال
عنوان ژورنال: Molecular Immunology
سال: 2014
ISSN: 0161-5890
DOI: 10.1016/j.molimm.2013.11.016